Fosamax, Aredia, Actonel or Zometa

Leading to Dead Jaw or Osteonecrosis of the Jaw

Fosamex is a prescription drug used to treat a variety of bone related conditions, it is a type of drug known as bisphosphonates. Fosamax was approved by the FDA in 1995. Fosamax and bisphosphonates are most commonly prescribed to prevent and treat osteoporosis in post-menopausal women. However, it is also approved to prevent and treat osteoporosis in both men and women, to treat Paget's disease of the bone, and to treat patients with cancer that has metastasized to the bone. It is estimated that doctors wrote 39 million prescriptions for Fosamax in American alone.

It has been discovered that there is a connection between Fosamax and a serious bone disease called osteonecrosis of the jaw (ONJ), which is also known as "dead jaw." ONJ is a condition in which the bone tissue in the jaw fails to heal after any minor trauma, such as a tooth extraction, causing the bone to be exposed. This exposure can lead to infection or fracture and can require surgery to remove the dying bone tissue. If you, a member of your family, or someone you know has experienced any problems, immediately contact the Law Offices of Nadrich & Cohen.

Nadrich & Cohen is investigating claims for Fosamax and Actonel users nationwide who have suffered damage to their jaw bone because of Fosamax. If you have been injured by Fosamax Actonel, Aredia, or Zometa, contact our Fosamax attorneys for a free legal consultation. You may be entitled to compensation for a jaw bone injury which could have been prevented.

In the U.S. Package Insert for both Aredia and Zometa, the following information on osteonecrosis has been added to the Adverse Reactions section under Post-Marketing Experience.

"Cases of osteonecrosis (primarily involving the jaws) have been reported in patients treated with bisphosphonates. The majority of the reported cases are in cancer patients attendant to a dental procedure. Osteonecrosis of the jaw has multiple well documented risk factors including a diagnosis of cancer, concomitant therapies (e.g., chemotherapy, radiotherapy, corticosteroids) and co-morbid conditions (e.g., anemia, coagulopathies, infection, pre-existing oral disease). Although causality cannot be determined, it is prudent to avoid dental surgery as recovery may be prolonged."

Biophosonates remain in the bones indefinitely. Fosamax, Aredia, Actonel and Zometa are in the class of drugs known as Biophosonates, they are also used in the management of certain cancers - such as multi myeloma - where the cancer has metastisized (spread) and is therefore used for bone, lung, prostate and breast cancer.

The problem with drugs such as Fosamax is that they can upset the delicate balance between the cells that place calcium in the bone and the cells that take calcium away. Unfortunately, osteoporosis of the jaw is a risk for all Biophosonates.

Osteonecrosis of the jaw

Osteonecrosis of the jaw is the destruction of bone tissue. It is also referred to as dead jaw, ONJ, Jaw Necrosis, or Bis-Pphosy jaw. The condition is a degenerative, deteriorative, and painful condition that involves soft tissue swelling in the mouth, loosening of the teeth, drainage, infection, and subsequently exposed bone. It is the result of blood flow not properly reaching the jaw bone. This painful and disfiguring condition causes the jaw bone to decay and die.

Fosamax Fractured Femur

There have been numerous medical studies linking Fosamex to fractured femurs. Long term Fosamex use often causes the dense bone in the femur to become brittle and break easier. We are presently investigating from coast to coast numerous cases of women who suffered leg fractures and had to have surgery due to their Fosamex use.  Studies have indicated that Fosamex users are 139 times more likely to develop femur fractures than non-Fosamex using women.

    We are actively investigating fractured femur claims of long-term Fosamex users who have broken their leg/femur and had surgery. If you or a loved one fractured their femur while on Fosamex, please have them call one of our Fosamex team members at 800-718-4658 or complete the email questionnaire on your right. A team member will respond immediately. We are handling Fosamex fracture femur cases from coast to coast.

Merck, Failure To Warn

The manufacturer of Fosamax, Merck, failed to warn users of the side effects. Many believe Merck was more concerned with protecting its profits than protecting the health of Fosamax users.

Free consultation.

If you have been injured by Fosamax, Actonel, Aredia, or Zometa, contact our experienced Fosamax Attorneys at the Law Offices of Nadrich & Cohen for a free consultation. Please complete the below client inquiry and send to us. We promise to respond within 24 hours.

There is no cost or obligation to contact an attorney at Nadrich & Cohen. We handle all inquiries with the strictest confidence and sensitivity. Inquiries in Canada and other nations are welcome. If our 800 number does not work from your country, please call us at (310)826-8082.