Popular Diabetes Drugs Receive FDA Warning of Ketoacidosis Risk

FDA Warning for Jardiance Farxiga InvokanaThere are many drugs on the market that help diabetes patients manage their blood sugar levels so that they don’t suffer from life-threatening complications. However, these same drugs have been under scrutiny for causing serious health conditions. In fact, the Food and Drug Administration (FDA) recently added additional warnings to several popular Type 2 diabetes medications.

Invokana, Jardiance and Farxiga, also called sodium-glucose cotransporter-2 (SGLT2) inhibitors, are prescribed to patients who have Type 2 diabetes and are recommended for use in conjunction with a diet and exercise program. They all carry a high risk of ketoacidosis, a serious condition that causes the body to burn fat for energy. When this process occurs, the body produces dangerous chemicals called ketones. Elevated ketone levels can lead to coma or even death. Onset of ketoacidosis can occur within a matter of hours. Initial symptoms include: dry mouth, excessive thirst, frequent urination and high glucose levels. Patients may also experience fatigue, vomiting, abdominal pain and breathing difficulties. The FDA warning notes that high blood glucose levels do not need to be present in order for ketoacidosis to occur. These drugs also carry an increased risk of urinary tract infections (UTIs.) In many cases, UTIs can develop into serious kidney and blood infections requiring hospitalization and even dialysis.

The FDA is requiring that additional warnings be added to all drugs containing the ingredients empagliflozin, canagliflozin or dapagliflozin. The warning comes as a response to the seventy-three adverse event reports that the FDA received, across a two-year time span. The reports indicate a ketoacidosis diagnosis among patients who were using SGLT2 medications. Between March 2013 and October 2014, another nineteen patients reported being hospitalized to treat serious kidney infections and blood infections, believed to be linked to SGLT2 usage. ent FDA warning is a follow-up to its safety review in May 2015, wherein a Drug Safety Communication was released notifying patients and doctors of the ketoacidosis risk.

If you or a loved one have been diagnosied with ketoacidosis while taking Invokana, Invokamet, Jardiance or Farxiga, contact the dangerous drug lawyers of Nadrich & Cohen, LLP for a free consultation. There are strict time limits for making a claim. Call today for a free consultation with one of our dangerous drug specialists.

Do I Have A Case?

We offer free consultation. No office visit required, we will get back to you within 24 hours.

  • This field is for validation purposes and should be left unchanged.


What can we do for you?

  • Answer your legal question.
  • Provide a Free Case Evaluation.
  • Schedule an appointment.


Choose Us?

  • Available 24/7
  • Trusted Since 1990
  • Local to You
  • Recovered $350,000,000
  • 5 Star Reviews
  • Free Case Evaluation
  • VIP Service
  • No Win, No Fee

Latest Law Post

May 8, 2019

Best Bike Cities 2019

The California cities of Santa Barbara, Santa Monica, San Diego, Ventura, Lompoc, Goleta, Santa Maria, Long Beach and Carpinteria were all in the top 50 best overall cities for bicycling compiled by People For Bikes in May 2019. Santa Barbara was ranked the highest of all California cities, in 12th place.

May 1, 2019

Understanding Car Insurance Costs

Before buying a new car, you may want to consider all costs of owning a vehicle not just your monthly car payment. One of the biggest expenses associated with owning or leasing a car, besides the monthly car payment, is insurance. In some cases, insurance can cost as much or even more than your car payment.


We are Personal Injury Lawyers representing accident victims throughout California.
For 30 years, the law firm of Nadrich & Cohen, LLP has helped injury victims
obtain the compensation they deserve.